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KIT and FLT3 receptor tyrosine kinase mutations in acute myeloid leukemia with favorable cytogenetics: Two novel mutations and selective occurrence in leukemia subtypes and age groups

✍ Scribed by Narongrit Sritana; Chirayu U. Auewarakul


Book ID
113956588
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
863 KB
Volume
85
Category
Article
ISSN
0014-4800

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## Abstract ## BACKGROUND The clinical relevance of mutations of the __FMS__‐like tyrosine kinase 3 (__FLT3__) gene in specific cytogenetic subgroups is not clear. The authors examined internal tandem duplication (ITD) and Asp835 mutations of __FLT3__ in patients with acute promyelocytic leukemia