## Background: The presence of regional metastasis in patients with head and neck squamous cell carcinoma (hnscc) is a common and adverse event associated with poor prognosis and high mortality. although significant improvements in standard therapies have increased the efficacy of local tumor manag
KiSS1 mediates platinum sensitivity and metastasis suppression in head and neck squamous cell carcinoma
β Scribed by Jiffar, T; Yilmaz, T; Lee, J; Hanna, E; El-Naggar, A; Yu, D; Myers, J N; Kupferman, M E
- Book ID
- 109972891
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 664 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0950-9232
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## Background: Squamous cell carcinoma (scc) of the head and neck region is rare in young patients and even less frequent in children 15 years or younger children. the patients reported in the literature are isolated cases and their management is always difficult because there is no large experienc
## Abstract Comparative genomic hybridization (CGH) was used to detect chromosomal changes during metastasis formation of head and neck squamous cell carcinomas (HNSCCs). In total, 92 tumors of 54 patients were investigated. In 34 of these, the metastases were compared to the corresponding primary