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KIR2DL5 alleles mark certain combination of activating KIR genes

✍ Scribed by Du, Z; Sharma, S K; Spellman, S; Reed, E F; Rajalingam, R

Book ID
109852803
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
224 KB
Volume
9
Category
Article
ISSN
1466-4879

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## Abstract NK cells detect altered patterns of HLA expression in infections and tumors using a variegated repertoire of killer cell Ig‐like receptors (KIR). Each clone surveys different HLA molecules by expressing a limited subset of the KIR encoded in its genome, which is maintained throughout ce