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Kinked DNA in crystalline complex with EcoRI endonuclease

✍ Scribed by Frederick, Christin A.; Grable, John; Melia, Michele; Samudzi, Cleopas; Jen-Jacobson, Linda; Wang, Bi-Cheng; Greene, Patricia; Boyer, Herbert W.; Rosenberg, John M.

Book ID
109735553
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
644 KB
Volume
309
Category
Article
ISSN
0028-0836

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Free Energy Analysis of Protein–DNA Bind
Free Energy Analysis of Protein–DNA Binding: The EcoRI Endonuclease–DNA Complex
✍ B Jayaram; K.J McConnell; Surjit B Dixit; D.L Beveridge πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 375 KB

A detailed theoretical analysis of the thermodynamics and functional energetics of protein-DNA binding in the EcoRI endonuclease-DNA complex is presented. The standard free energy of complexation is considered in terms of a thermodynamic cycle of seven distinct steps decomposed into a total of 24 we