Kinetics versus Thermodynamics in Protein Folding
β Scribed by Baker, David; Agard, David A.
- Book ID
- 120600299
- Publisher
- American Chemical Society
- Year
- 1994
- Tongue
- English
- Weight
- 612 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0006-2960
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This article appeals to an evolutionary model which postulates that primordial proteins were described by small polypeptide chains which (i) lack disulfide bridges, and (ii) display slow folding rates with multi-state kinetics, to determine relations between structural properties of proteins and the
The most surprising feature of proteins, which distinguishes them from all other types of large polymeric molecules and provides them with a broad range of special properties, is their unique structural order. The position of each atom in these macromolecules is unique relative to its neighboring at