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Kinetics of uptake of 2-deoxy-d-glucose and 2-aminoisobutyric acid in chemically transformed cells

✍ Scribed by Toshio Kuroki; Shigeyo Yamakawa

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
401 KB
Volume
13
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Kinetics of 2‐deoxy‐D‐glucose and 2‐aminoisobutyric acid uptake in chemically transformed hamster embryo cells and BALB 3T3 cells were investigated. Maximum velocity of the glucose uptake in chemically transformed cells increased 1.5 to 2.8‐fold over controls in Vmax without a detectable change in apparent Km. In uptake of the amino acid there was a slight change in Vmax and unchanged Km with chemically transformed cells, as compared to untransformed cells. Hexokinase activity showed a slight change after chemical transformation.

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