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Kinetics of Two Slow Conformational Transitions of the Quadruplex Structure of the Thrombin Binding Aptamer and their Potassium Dependence

✍ Scribed by Ranpura, Harikrushan; Bolton, Philp H.


Book ID
123439693
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
73 KB
Volume
106
Category
Article
ISSN
0006-3495

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## Abstract The dual‐labeled oligonucleotide derivative, FAT‐0, carrying 6‐ carboxyfluorescein (FAM) and 6‐carboxytetramethylrhodamine (TAMRA) labels at the 5′ and 3′ termini of the thrombin‐binding aptamer (TBA) sequence 5′‐GGT TGG TGT GGT TGG‐3′, and its derivatives, FAT‐__n__ (__n__=3, 5, and 7)