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Kinetics of phenylalanine transport at the human blood–brain barrier investigated in vivo

✍ Scribed by Harald E Möller; Josef Weglage; Dirk Wiedermann; Peter Vermathen; Ulrich Bick; Kurt Ullrich


Book ID
114003246
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
765 KB
Volume
778
Category
Article
ISSN
0006-8993

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Regional transport of phenylalanine acro
✍ Michael Pollay 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 476 KB

## Abstract In adult rats, using the single‐pass brain uptake technique with a tritiated water standard, L‐phenylalanine was shown to enter brain across the blood‐brain barrier (BBB) by both a saturable and diffusionary process. A kinetic analysis of the data revealed Michaelis constant (K~a~) of 0