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Kinetics of oral and intravenous mexiletine: lack of effect of cimetidine and ranitidine

✍ Scribed by N. H. Brockmeyer; H. Breithaupt; W. Ferdinand; M. Hattingberg; E. E. Ohnhaus

Publisher
Springer
Year
1989
Tongue
English
Weight
649 KB
Volume
36
Category
Article
ISSN
0031-6970

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The effects of three gastric antisecretory drugs on the pharmacokinetics of ethanol have been studied in a randomized crossover experiment. Male medical students (n = 12) took ethanol 0.8 g/kg body weight at 08.00 h after an overnight fast. On seven successive days before drinking ethanol they were