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Kinetics of irreversible enzyme inhibition: The tsou plot in irreversible binding co-operativity

โœ Scribed by Emmanuel T. Rakitzis

Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
231 KB
Volume
70
Category
Article
ISSN
0022-5193

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Kinetics of substrate reaction during irreversible modification of enzyme activity where the modifier is not in great excess of the enzyme
โœ Kang-Yuan Zhao; Chen-Lu Tsou ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 586 KB

The kinetic approach previously developed (Tsou 1988, Adv. Enzymok 61,381-386) for the substrate reaction in the presence of modifier is based on the supposition that [Yo]>> [Eo]. However, the presence of the modifier in large excess of the enzyme sometimes leads to a rate of modification which is t