Kinetics of hydrochlorothiazide absorption in humans
โ Scribed by Elliot Redalieu; Keith K. H. Chan; Vijay Tipnis; Sylvia B. Zak; Thomas G. Gilleran; William E. Wagner Jr.; Ann R. Lesher
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 273 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0022-3549
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๐ SIMILAR VOLUMES
A method for determining plasma hydrochlorothiazide levels was developed with a sensitivity of 5 ng/ml. Accuracy and precision were demonstrated over the 5--648-ng/ml range by an overall recovery of 95 +/- 8%. The detector response was linear for the 5--250-ng/ml range. The method was sufficiently s
By using the GI tube technique, niacin was shown to be equally well absorbed from the stomach and the upper small intestine. The maximum plasma niacin concentrations occurred 10-20 and 5-10 min, respectively, after instillation. Thus, the physiological prerequisites for a physically retarded niacin