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Kinetics of expression analysis during myc-mediated apoptosis

✍ Scribed by Holzmann, Klaus; Schamberger, Chantal; Schmidt, Gerlinde; Skrzypek, Barbara; Sasgary, Soleman; Cerni, Christa

Book ID
109830424
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
29 KB
Volume
27
Category
Article
ISSN
1061-4036

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## Abstract Mad proteins (Mad1, Mxi1, Mad3, Mad4, Mnt/Rox) are biochemical and biological antagonists of c‐Myc oncoprotein. Mad‐Max dimers repress the transcription of the same target genes activated by Myc‐Max dimers. Despite the critical role of Max and Mad proteins as modulators of c‐Myc functio