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Kinetics of ddI in Plasma, Brain, and CSF of Rats after Administration of ddI and an Ester Prodrug of ddI

โœ Scribed by BRADLEY D. ANDERSON; BARBARA L. HOESTEREY; DAVID C. BAKER; RAYMOND E. GALINSKY


Book ID
119864136
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
125 KB
Volume
616
Category
Article
ISSN
0890-6564

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## Abstract D, Lโ€3โ€hydroxyโ€3โ€ethylโ€3โ€phenylpropanamide (HEPP) is a synthetic drug with anticovulsant effects in a variety of seizure models. HEPP pharmacokinetics was studied after single 50 mg kg^โˆ’1^ intravenous (IV), intraperitoneal (IP), and oral (PO) administration in male albino Wistar rats. T