Kinetics of cholinesterase inhibition by eptastigmine in man
β Scribed by L. K. Unni; V. Hutt; B. P. Imbimbo; R. E. Becker
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 187 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0031-6970
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The effect of galanthamine (GAL) and its 2 major metabolites on human cholinesterases has been explored. Epigalanthamine, a diastereomer of GAL, was 130-times less potent in vitro in its effect on acetylcholinesterase (AChE) in erythrocytes than the parent compound, and it did not differ significant
## Abstract Metoclopramide (MCP) is a dopamine receptor antagonist and serotonine receptor agonist widely used as an antiemetic and gastric prokinetic drug. In addition MCP is a reversible inhibitor of cholinesterases from human central nervous system and blood. MCP may have a cholinesterase protec
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