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Kinetics of aggrecanase- and metalloproteinase-induced neoepitopes in various stages of cartilage destruction in murine arthritis

✍ Scribed by Joyce B. J. Van Meurs; Peter L. E. M. Van Lent; Astrid E. M. Holthuysen; Irwin I. Singer; Ellen K. Bayne; Wim B. Van Den Berg


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
439 KB
Volume
42
Category
Article
ISSN
0004-3591

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## Abstract ## Objective Previously, we reported that interferon‐γ (IFNγ) aggravates cartilage destruction in immune complex (IC)–mediated arthritis via up‐regulation of activating Fcγ receptors (FcγR). Recently, we found that interleukin‐17 (IL‐17) also aggravates cartilage destruction in arthrit