Synthesis and preliminary evaluation of
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Rebecca A. Wallace; Joe P. Haar Jr.; Donald B. Miller; Steven R. Woulfe; John A.
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Article
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1998
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John Wiley and Sons
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English
⚖ 724 KB
## Abstract A nonaromatic, small‐molecule, gadolinium(3+)‐chelate code named MP‐2269 was synthesized and evaluated in animals as a potential MR contrast agent for blood pool. The ligand of MP‐2269 was prepared by conjugating a lipophilic, albumin‐binding moiety, 4‐pentylbicyclo[2.2.2]octane‐1‐carbo