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Kinetics and Mechanism of the (−)-Sparteine-Mediated Deprotonation of ( E )- N -Boc- N -( p -methoxyphenyl)-3-cyclohexylallylamine

✍ Scribed by Pippel, Daniel J.; Weisenburger, Gerald A.; Faibish, Neil C.; Beak, Peter


Book ID
126835561
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
251 KB
Volume
123
Category
Article
ISSN
0002-7863

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Chiral diamines. Part 3: Effect of ligan
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The deprotonation N-Boc-pyrrolidine by i-PrLi-(S,S)-1,2-bis(N,N-dimethylamino)cyclohexane has been studied at the HF/3-21G and B3P86/6-31G\* theoretical levels. The two lowest energy complexes of the N-Boc-pyrrolidine-i-PrLi-diamine ligand, as well as the transition states leading to proton transfer