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Kinetics and mechanism of colchicine binding to tubulin: evidence for ligand-induced conformational changes

✍ Scribed by Garland, Donita L.


Book ID
121089316
Publisher
American Chemical Society
Year
1978
Tongue
English
Weight
830 KB
Volume
17
Category
Article
ISSN
0006-2960

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Ligand-Induced conformational changes in
✍ Jianhua Wu; Stathis Frillingos; John Voss; H. Ronald Kaback πŸ“‚ Article πŸ“… 1994 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 848 KB

## Abstract By using a lactose permease mutant containing a single Cys residue in place of Val 331 (helix X), conformational changes induced by ligand binding were studied. With right‐side‐out membrane vesicles containing Val 331 β†’ Cys permease, lactose transport is inactivated by either __N__‐ethy