## Abstract A kinetic study on hydrolysis of Nβ(2β²βhydroxyphenyl)phthalamic acid (**1**), Nβ(2β²βmethoxyphenyl)phthalamic acid (**2**), and Nβ(2β²βmethoxyphenyl)benzamide (**3**) under a highly alkaline medium gives secondβorder rate constants, __k__~OH~, for the reactions of HO^β^ with **1, 2**, and
Kinetics and mechanism of alkaline hydrolysis of N-(2-bromoethyl)phthalamic acid
β Scribed by Khan, M. Niyaz
- Book ID
- 125897356
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 289 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
The aqueous cleavage of N-(2-bromoethyl)phthalimide (NBEPH), N-(3-bromopropyl)phth&mide (NBPPH), and N-carbethoxyphthalimide (NCPH) have been studied within the [OH] range of 5 x 10 M to 2 x 10.' M, pH range of 8.82 to 10.62 and 8.06 to 8.66, respective1y:The observed pseudo-first-order rate consta
of the acetyl group had an overall negative effect on the antimalarial potency of this series of thiosemicarbazones. Antibacterial Activity-In the assessment of the antibacterial activity of the 2-(a-hydroxyacetyl)pyridine thiosemicarbazones (Table Ill), the strong inhibitory effect of the 2-acetyl