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Kinetics and mechanism of alkaline hydrolysis of N-(2-bromoethyl)phthalamic acid

✍ Scribed by Khan, M. Niyaz


Book ID
125897356
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
289 KB
Volume
50
Category
Article
ISSN
0022-3263

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πŸ“œ SIMILAR VOLUMES


Kinetics and mechanism of hydrolysis of
✍ Yoke-Leng Sim; Emmy Fadhiza Damit; Azhar Ariffin; M. Niyaz Khan πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 160 KB

## Abstract A kinetic study on hydrolysis of N‐(2′‐hydroxyphenyl)phthalamic acid (**1**), N‐(2′‐methoxyphenyl)phthalamic acid (**2**), and N‐(2′‐methoxyphenyl)benzamide (**3**) under a highly alkaline medium gives second‐order rate constants, __k__~OH~, for the reactions of HO^βˆ’^ with **1, 2**, and

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The aqueous cleavage of N-(2-bromoethyl)phthalimide (NBEPH), N-(3-bromopropyl)phth&mide (NBPPH), and N-carbethoxyphthalimide (NCPH) have been studied within the [OH] range of 5 x 10 M to 2 x 10.' M, pH range of 8.82 to 10.62 and 8.06 to 8.66, respective1y:The observed pseudo-first-order rate consta

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of the acetyl group had an overall negative effect on the antimalarial potency of this series of thiosemicarbazones. Antibacterial Activity-In the assessment of the antibacterial activity of the 2-(a-hydroxyacetyl)pyridine thiosemicarbazones (Table Ill), the strong inhibitory effect of the 2-acetyl