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Kinetics and Energetics of Biomolecular Folding and Binding

✍ Scribed by Pierse, Christopher A.; Dudko, Olga


Book ID
123049034
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
84 KB
Volume
106
Category
Article
ISSN
0006-3495

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The available experimental data on the kinetics of unfolding and refolding of small proteins are reviewed. Excluding slow transitions in the unfolded protein due to cis- trans isomerization of peptide bonds, the rate-limiting transition state in both unfolding and refolding is concluded to be a high