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Kinetics and dynamics of enalapril in patients with liver cirrhosis

✍ Scribed by Ohnishi, Akihiro; Tsuboi, Yoshimasa; Ishizaki, Takashi; Kubota, Kiyoshi; Ohno, Toshiyuki; Yoshida, Hiroshi; Kanezaki, Akira; Tanaka, Teruji


Book ID
109844701
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
715 KB
Volume
45
Category
Article
ISSN
0009-9236

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Cimetidine Kinetics and Dynamics in Pati
✍ Jean-Pierre Villeneuve; HΓ©lΓ¨ne Fortunet-Fouin; Dominique ArsΓ¨ne πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 536 KB

Following cimetidine administration, 60% of the dose is excreted as unchanged drug in the urine, and 40% is eliminated by metabolism. We evaluated the effect of liver disease on cimetidine disposition by comparing its kinetics in 7 healthy subjects and 8 patients with alcoholic cirrhosis. Cirrhotic