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Kinetic α-deuterium isotope effects for enzymatic and nonenzymatic hydrolysis of nicotinamide-β-riboside

✍ Scribed by Julio P. Ferraz; Herbert G. Bull; Eugene H. Cordes


Book ID
115703826
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
550 KB
Volume
191
Category
Article
ISSN
0003-9861

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A very high S-deuterium kinetic isotope effect, k(CH3)/k(CD3) =2.l3 at ~o'c, was found for the solvolysis of 2-(3'-chlorophenyl)-l,l,l-trifluoro-2propyl tosylate(&) and the a-CD3 analogue