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Kinetic study of the effects of extracts from Vicia faba var. equina on intestinal sugar absorption

✍ Scribed by Yolanda Barcina; Ana I. Alcalde; Anunciación Ilundain; Jesús Larralde


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
570 KB
Volume
35
Category
Article
ISSN
0022-5142

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✦ Synopsis


Alcoholic and water extracts from seed-coats of Viciafaba var. equina were prepared and their effects on in-vivo intestinal sugar absorption across the rat small intestine were investigated. Both extracts significantly (P<O.OOl) inhibited sugar absorption. The higher and more stable inhibition was induced by the water extract. Pretreatment of the extracts with polyamide significantly (P<O.OOl) reduced their inhibitory potency but did not abolish it, suggesting the presence in the extracts of some other intestinal sugar absorption inhibitor, different from polyphenols. Although both extracts inhibited intestinal sugar active transport, only the water extract was able to reduce sugar diffusion across the small intestine. These differences in behaviour seem to be related to the polyphenolic content of each extract.


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