Kinetic study of 11β-hydroxysteroid dehydrogenase in rat submandibular salivary gland
✍ Scribed by M.M. Ferguson; G.B. MacPhee
- Book ID
- 115710879
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- English
- Weight
- 471 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0003-9969
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## Abstract Renal 11β‐hydroxysteroid dehydrogenase 2 (HSD2) catalyzes the conversion of active glucocorticoids to inert 11β‐keto compounds, thereby preventing the illicit binding of these hormones to mineralocorticoid receptors (MRs) and, thus, conferring aldosterone specificity. Absence or inhibit