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Kinetic Studies of the Interaction between Rifampicin and DNA-Dependent RNA Polymerase of Escherichia coli

โœ Scribed by Walter WEHRLI


Book ID
118701361
Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
526 KB
Volume
80
Category
Article
ISSN
1432-1327

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Rifampicin inhibits bacterial DNA-dependent RNA polymerase by forming a l:l complex with the enzyme. In previous studies the extent of this binding was determined by chromatographic isolation of the complex on Sephadex columns with t4C-labeled rifampicin as tracer, To measure the kinetics of the enz