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Kinetic studies of normal and variant hypoxanthine phosphoribosyltransferases in intact fibroblasts

โœ Scribed by Theodore Page; Bohdan Bakay; William L. Nyhan


Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
311 KB
Volume
122
Category
Article
ISSN
0003-2697

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โœฆ Synopsis


The instability of many mutant enzymes prevents their study by classical in vitro techniques.


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Growth kinetics and collagen synthesis o
โœ Robert F. Diegelmann; I. Kelman Cohen; Barbara J. McCoy ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 461 KB

## Abstract Fibroblasts were isolated from keloid, normal skin, and normal scar and maintained in tissue culture for four passages. Growth kinetics were the same for all groups on days 2 through 12. However, the rate of collagen synthesis per fibroblast was greater in keloid derived cells than any