Kinetic resolutions: evaluation of a one dimensional E value calculation method using a computer and statistical software
✍ Scribed by Milton J Zmijewski; Gary Sullivan; Rose Persichetti; Jim Lalonde
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 248 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0957-4166
No coin nor oath required. For personal study only.
✦ Synopsis
A recently published curve fitting method of determining E values was put to the test using a computer and statistical software. Using idealized data and curves, the methodology worked reasonably well. Confidence limits generated by the ideal data were still large. However, when real data were employed, this methodology was not satisfactory in generating reliable E values due to inherent errors in the progress curves generated. This approach does not appear to be suitable for determining E values from one dimensional progress curves even when powerful statistical software and a computer are used to evaluate the data.