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Kinetic Resolution of α-Substituted Alkanoic Acids Promoted by Homobenzotetramisole

✍ Scribed by Xing Yang; Prof. Vladimir B. Birman

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
413 KB
Volume
17
Category
Article
ISSN
0947-6539

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The lipase-catalyzed acetylation of a broad spectrum of configurations of the 2-hydroxy acids 1 were assigned by comparison of the gas-chromatographic data with that of racemic 2-hydroxy acids 1 to their 2-acetoxy acids 2 was shown to proceed with high enantioselectivity. Thus, the literature-known