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Kinetic Resolution of Racemic Carboxylic Acids by an l -Histidine-Derived Sulfonamide-Induced Enantioselective Esterification Reaction

✍ Scribed by Ishihara, Kazuaki; Kosugi, Yuji; Umemura, Shuhei; Sakakura, Akira


Book ID
120026181
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
227 KB
Volume
10
Category
Article
ISSN
1523-7060

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Resolution of racemic carboxylic acid de
✍ Dieter Seebach; Georg Jaeschke; Konstanze Gottwald; Keiji Matsuda; Roberto Formi πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 909 KB

The Lewis-acid mediated transfer of an alkoxide ligand from the chiral ligand sphere of Ti-TADDOLates ! to cyclic carboxylic acid derivatives is described. The kinetic resolution of dioxolanones, azlactones and biaryl lactones by the Ti-TADDOLates affords, after recrystallization, ester products in