Kinetic resolution of α-acetoxy carboxyl
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Sean P. Bew; Stephen G. Davies; Shin-ichi Fukuzawa
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Article
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2000
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John Wiley and Sons
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English
⚖ 130 KB
Preliminary investigations focused on the kinetic resolution of (+/-)-alpha-acetoxy mandelic carboxylic acid chloride with isopropyl SuperQuat and isopropyl Evans' homochiral auxiliaries. The addition of 2 equiv. of the acid chloride to the lithium salts of the auxiliaries (SuperQuat and Evans') at