Enantioselective deprotonation of 4-substituted cyclohexanones (1) in the presence of excess trimethylsilyl chloride was examined using chirai bidentate lithium amides ((R)-3~(R)-7) in THF. The solution structures of (R)-3a in THF in the presence and in the absence of lithium chloride were studied b
Kinetic resolution of racemic 2-substituted cyclohexanones by enantioselective deprotonation
β Scribed by Hee-doo Kim; Hisashi Kawasaki; Makoto Nakajima; Kenji Koga
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 226 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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## Stereochemistry of Enantioselective Deprotonation of 4-Substituted Cyclohexanones by Chiral Bidentate Lithium Amides. -Enantioselective deprotonation of 4-substituted cyclohexanones using chiral lithium amide bases such as (I) in the presence of excess trimethylsilyl chloride results in format
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