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Kinetic properties and regulation of biliverdin reductase

✍ Scribed by J.Ellis Bell; Mahin D. Maines


Book ID
115707949
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
793 KB
Volume
263
Category
Article
ISSN
0003-9861

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## Abstract hBVR functions in the cell as a reductase and as a kinase. In the first capacity, it reduces biliverdin, the product of HO activity, to the effective intracellular antioxidant, bilirubin; as a dual‐specificity kinase (S/T/Y) it activates the MAPK and IGF/IRK receptor signal transduction