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Kinetic Effects of ATP and Two Cellular Stimulatory Components on Human Leukocyte 5-Lipoxygenase

โœ Scribed by CAROL A. ROUZER; NANCY A. THORNBERRY; HERBERT G. BULL


Book ID
119862001
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
563 KB
Volume
524
Category
Article
ISSN
0890-6564

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โœ L. Iversen; K. Fogh; K. Kragballe ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 478 KB

The purpose of the present study was to determine the effect of the n-6 fatty acid, dihomogammalinolenic acid (DGLA, 20 : 3, n-6) on arachidonic acid (AA) (C20:4) metabolism by human peripheral mononuclear leukocytes (HPML). After incubation of HPML with A23187 (5 ~tM) and DGLA, the cyclooxygenase (