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Kinetic difference of berberine between hippocampus and plasma in rat after intravenous administration of Coptidis rhizoma extract

✍ Scribed by Xueli Wang; Rufeng Wang; Dongming Xing; Hui Su; Chao Ma; Yi Ding; Lijun Du

Book ID
116718001
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
236 KB
Volume
77
Category
Article
ISSN
0024-3205

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## Abstract D, L‐3‐hydroxy‐3‐ethyl‐3‐phenylpropanamide (HEPP) is a synthetic drug with anticovulsant effects in a variety of seizure models. HEPP pharmacokinetics was studied after single 50 mg kg^−1^ intravenous (IV), intraperitoneal (IP), and oral (PO) administration in male albino Wistar rats. T