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Kinetic description of proteolysis. Part 1. Peptic hydrolysis of proteins isolated from chicken heart: Optimization in terms of time and substrate concentration

✍ Scribed by Belikov, V. M. ;Kudinova, E. G. ;Vorob'Ev, M. M.


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
253 KB
Volume
30
Category
Article
ISSN
0027-769X

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✦ Synopsis


Simple equation for the total rate of proteolysis is proposed. The equation. based on the real mechanism of proteolysis includes the substrate concentration and some functions of the degree of hydrolysis. These functions are experimentally determined in the case of peptic hydrolysis of chicken heart proteins. The integration ofdifferential equation made it possible to describe thc kinetics of the proteolysis in terms of substrate conccntration, degree ofproteolysis and reaction time. The kincticsofproteolysisdocs not obey the MIcf[,wI.