Kinetic characterization of sulphur-containing excitatory amino acid uptake in primary cultures of neurons and astrocytes
β Scribed by Grieve, Angus; Dunlop, John; Schousboe, Arne; Griffiths, Roger
- Book ID
- 121772506
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 728 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0197-0186
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Uptake and oxidative metabolism of [I4C]malate as well as its incorporation into aspartate, glutamate, glutamine, and GABA were studied in cultured cerebral cortical neurons (GABAergic), cerebellar granule neurons (glutamatergic), and cerebral cortical astrocytes. All cell types exhibited high affin
## Abstract ^3^HβDβAspartate uptake was biochemically characterized in cultures from chick retina enriched in glial (MΓΌller) cells or neurons during progressive days in vitro (DIV). In the neuronal cultures a highβaffinity, Na+βdependent system was found with Km = 8β13 ΞΌM and pharmacological charac