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Kinetic and structural analysis of succinate:ubiquinone oxidoreductase (complex II) inhibition by thiapronil

✍ Scribed by Domenik Lisse; Li-shar Huang; Thorsten Gasteiger; Edward A. Berry; Peter Lümmen


Book ID
113484616
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
79 KB
Volume
1797
Category
Article
ISSN
0005-2728

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Kinetic microplate-based assays for both mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:cytochrome c oxidoreductase using insect submitochondrial particles as the source of the enzyme activities have been developed. These assays have been used to design high-throughput screen