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Kinetic and Safety Studies on Intrathecally Infused Recombinant-Methionyl Human Brain-Derived Neurotrophic Factor in Dogs

✍ Scribed by Tony L. Yaksh; Michael L. Rathbun; Jean C. Dragani; Shelle Malkmus; Amy R. Bourdeau; Philip Richter; Harry Powell; Robert R. Myers; Carl P. Lebel


Book ID
115608790
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
756 KB
Volume
38
Category
Article
ISSN
0272-0590

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## Abstract Recombinant human brain‐derived neurotrophic factor (BDNF) is now under extensive investigation because of its potential clinical applications. Radioactively labeled proteins are usually required to study receptor binding and pharmacokinetic properties of proteins. This study was undert