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Kinetic and metabolic evaluation of new PET ligands for peripheral benzodiazepine receptors

✍ Scribed by M. Imaizumi; E. Briard; S. Zoghbi; J. Hong; J. Shah; J. Musachio; V. Pike; R. Innis; M. Fujita

Book ID: 118490042
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 47 KB
Volume: 31
Category: Article
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2006.04.119

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## Abstract The peripheral benzodiazepine receptor (PBR) is expressed by microglial cells in many neuropathologies involving neuroinflammation. PK11195, the reference compound for PBR, is used for positron emission tomography (PET) imaging but has a limited capacity to quantify PBR expression. Here