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Kinetic analysis of the elimination process of human epidermal growth factor (hEGF) in rats

โœ Scribed by Dong Chool Kim; Sugiyama Yuichi; Fuwa Tohru; Sakamoto Shunji; Iga Tatsuji; Hanano Manabu


Book ID
115780782
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
979 KB
Volume
38
Category
Article
ISSN
0006-2952

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Kinetic analysis of the tissue distribution of human epidermal growth factor (hEGF) in rats was performed in vivo. The plasma disappearance half-life of [125I]hEGF was prolonged by coadministration of unlabeled hEGF, indicating saturation of the mechanism for hEGF removal from the systemic circulati