Kinetic analysis of relationship between partition coefficient and biological response
β Scribed by Eugene R. Cooper; Bret Berner; Robert D. Bruce
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 263 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0022-3549
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π SIMILAR VOLUMES
Partition coefficients (benzene/water) of members of a series of carbamoylpiper. idinodecanes have been determined. A parallel was observed between this property and the ability of the compounds to inhibit human plasma pseudo-cholinesterase.
Ostwald partition coefficients for mercury (HeZo3) vapor (ng Hg per ml fluid/ng Hg vapor per ml air) were determined for human whole blood, 10.50 (lOΒ°C), 6.62 (22"C), 4.20 (37Β°C); for human plasma, 5.56 (10 "C), 3.63 (22 "C), 2.40 (37 "C); for 0.9% NaC1; 2.65 (22 "C); and for sunflower oil, 80.8 (22
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