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Kinetic Analysis and Binding Studies of Proteins Bound to Planar Surfaces with CLSM

✍ Scribed by Ghafari, Homanaz; Parambath, Mithun; Hanley, Quentin


Book ID
119209380
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
37 KB
Volume
102
Category
Article
ISSN
0006-3495

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The loading of Ku onto a DNA end in a double-strand DNA break is thought to be one of the "rst steps in the non-homologous DNA end joining (NHEJ) pathway, giving it an essential role in the maintenance of genomic integrity. The binding of Ku to DNA is complicated since DNA can accommodate multiple K