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Kinesin II is required for cell survival and adherens junction positioning in Drosophila photoreceptors

✍ Scribed by Bibhash Mukhopadhyay; Sang-Chul Nam; Kwang-Wook Choi


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
161 KB
Volume
48
Category
Article
ISSN
1526-954X

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✦ Synopsis


Abstract

Genetic analysis of klp64D(kif3a homolog) function in the Drosophilapupal retina. The ommatidum on the left consists of wild‐type photoreceptors. The ommatidium on the right is a genetic mosaic containing wild‐type and mutant cells marked by green fluorescent protein. __klp64D__mutant cells show mislocalization of adherens junction proteins, DE‐Cadherin and Armadillo (labeled by red and blue staining, respectively). See the article by Mukhopadhyay et al. in this issue.


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Kinesin II is required for cell survival
✍ Bibhash Mukhopadhyay; Sang-Chul Nam; Kwang-Wook Choi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 837 KB

## Abstract Photoreceptor morphogenesis requires specific and coordinated localization of junctional markers at different stages of development. Here, we provide evidence that __Drosophila__ Klp64D, a homolog of Kif3A motor subunit of the heterotrimeric Kinesin II complex, is essential for viabilit