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Kinematics of gait in Golden Retriever Muscular Dystrophy

✍ Scribed by Anthony P. Marsh; Joel D. Eggebeen; Joe N. Kornegay; Chad D. Markert; Martin K. Childers


Book ID
116794329
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
315 KB
Volume
20
Category
Article
ISSN
0960-8966

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Golden retriever muscular dystrophy (GRMD), the canine model of Duchenne muscular dystrophy (DMD), is caused by a splice site mutation in the dystrophin gene. This mutation predicts a premature termination codon in exon 8 and a peptide that is 5% the size of normal dystrophin. Western blot analysis