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Kinase inhibitors: Narrowing down the real targets

✍ Scribed by Daub, Henrik


Book ID
109913351
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
261 KB
Volume
6
Category
Article
ISSN
1552-4450

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This work describes the preparation of approximately 13,000 compounds for rapid identification of hits in high-throughput screening (HTS). These compounds were designed as potential serine/threonine or tyrosine kinase inhibitors. The library consists of various scaffolds, e.g., purines, oxindoles, a