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Kinase Activation through the High-Affinity Receptor for Immunoglobulin E

✍ Scribed by Rossella Paolini; Robert Numerof; Jean-Pierre Kinet


Book ID
115618362
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
543 KB
Volume
4
Category
Article
ISSN
1058-6687

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IgE dysregulation is a major pathogenic feature of atopic dermatitis and other IgE-mediated allergic diseases such as asthma and rhinitis. Allergen complexed to IgE binds to the high affinity receptor for IgE (Fc epsilon RI) on the surface of epidermal Langerhans cells, mast cells and basophils, tri