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Ki-ras oncogene activation in transplantable rat thyroid carcinoma induced by N-bis(2-hydroxypropyl)nitrosamine

✍ Scribed by Hiasa, Yoshio; Kitahori, Yoshiteru; Nakahashi, Kazuhiro; Yane, Katsunari; Konishi, Noboru; Lin, Jung-Chung; Okaichi, Kumio; Ohnishi, Takeo


Book ID
122603214
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
559 KB
Volume
83
Category
Article
ISSN
0304-3835

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ras Oncogene activation in mammary carci
✍ Shi-Jiang Lu; Michael C. Archer πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 590 KB

## Abstract The occurrence of Ha‐__ras__ and Ki‐__ras__ oncogenes was investigated in mammary tumors produced by treating genetically resistant Copenhagen (Cop) rats with __N__‐methyl‐__N__‐nitrosourea. G^35^A codon 12 mutations in both Ha‐__ras__ and Ki‐__ras__ genes were analyzed by a polymerase