Ki-ras codon 12 point mutational activation in Hong Kong colorectal carcinoma patients
β Scribed by Josephine Mun-Yee Ko; Michael Ho-Yin Cheung; Chow-Ming Wong; Kwok-Wai Lau; Cecilia Man-Ching Tang; Ming Wa Kwan; Maria Li Lung
- Book ID
- 117469237
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 195 KB
- Volume
- 134
- Category
- Article
- ISSN
- 0304-3835
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Renal mesenchymal tumors induced in F344 rats with methyl(methoxymethyl)nitrosamine (DMNβOMe) have previously been shown by our laboratory to contain transforming Kiβ__ras__ sequences, activated most commonly by a variety of codon 12 mutations. Further sequence analysis of one DMNβOMeβi
## Abstract Colorectal carcinogenesis is regarded as a multistep process resulting from accumulation of genetic alterations, including activation of protooncogenes and inactivation of tumor suppressor genes via signal transduction trigger the stageβwise progression to malignancy. The reported incid