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KGF increases keratinocyte proliferation in vitro

✍ Scribed by C.S. Sobral; L.M. Ferreira; A.G. Filho

Book ID: 116329911
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 66 KB
Volume: 33
Category: Article
ISSN: 0305-4179
DOI: 10.1016/j.burns.2006.10.323

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Human keratinocyte growth factor (KGF) is an epithelial cell specific mitogen which is secreted by normal stromal fibroblasts. In the present studies, we demonstrate that KGF is as potent as EGF in stimulating proliferation of primary or secondary human keratinocytes in tissue culture. Exposure of K