Keynote review: Histamine H3 receptor antagonists reach out for the clinic
β Scribed by Sylvain Celanire; Maikel Wijtmans; Patrice Talaga; Rob Leurs; Iwan J.P. de Esch
- Book ID
- 114385227
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 353 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1359-6446
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π SIMILAR VOLUMES
A pharmacophore model for histamine H3 ligands is derived that reveals the putative interaction of both H3 agonists and antagonists with an aspartate residue of the receptor. This interaction is determined by applying the density functional theory implemented in a program package adapted for paralle
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